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Global • 2026-10-31, 18:10 GMT • ~1 min read

Placenta protein may offer clues to early brain development

نال میں موجود پروٹین بچے کے دماغ کی نشوونما کے راز کھول سکتی ہے

प्लेसेंटा में मिला प्रोटीन शिशु के मस्तिष्क विकास के राज़ खोल सकता है

Placenta protein may offer clues to early brain development

Key points

اہم نکات

मुख्य बातें

  • Researchers at Virginia Tech's Fralin Biomedical Research Institute have identified a protein in the placenta that had not previously been found there and that plays a role in fetal blood-vessel development.
  • The protein, soluble platelet-derived growth factor receptor beta (sR-beta), was described in a study published in the journal Angiogenesis.
  • The team measured baseline levels of the protein in a healthy, developing placenta and found it is sensitive to oxygen.
  • ورجینیا ٹیک کے محققین نے نال میں ایک ایسا پروٹین دریافت کیا ہے جو پہلے وہاں نہیں پایا گیا تھا۔ اس پروٹین کا نام سولوایبل پلیٹلیٹ ڈرائیوڈ گروتھ فیکٹر ریسیپٹر بیٹا (ایس آر بیٹا) ہے اور یہ بچے کی خون کی نالیوں کی نشوونما میں کردار ادا کرتا ہے۔ یہ تحقیق جریدے اینجیوجینیسس میں شائع ہوئی ہے۔ محققین کا کہنا ہے کہ یہ پروٹین آکسیجن کے لیے حساس ہے اور اس کی مقدار میں کمی بیشی بچے کے دماغ کی خون کی نالیوں کی نشوونما کو متاثر کر سکتی ہے، جس سے دماغی خون بہنا یا آنکھوں کو نقصان جیسے مسائل پیدا ہو سکتے ہیں۔ مستقبل میں یہ پروٹین دماغی نشوونما کے مسائل کی ابتدائی علامت کے طور پر کام کر سکتا ہے اور پری ایکلیمپسیا جیسی حمل کی بیماریوں کے علاج کا نیا ہدف بھی بن سکتا ہے۔
  • वर्जीनिया टेक के शोधकर्ताओं ने प्लेसेंटा में एक ऐसा प्रोटीन खोजा है जो पहले वहाँ नहीं पाया गया था। इस प्रोटीन का नाम सॉल्युबल प्लेटलेट-डेराइव्ड ग्रोथ फैक्टर रिसेप्टर बीटा (एसआर-बीटा) है और यह शिशु की रक्त वाहिकाओं के विकास में भूमिका निभाता है। यह शोध एंजियोजेनेसिस पत्रिका में प्रकाशित हुआ है। शोधकर्ताओं का कहना है कि यह प्रोटीन ऑक्सीजन के प्रति संवेदनशील है और इसकी मात्रा में कमी या अधिकता शिशु के मस्तिष्क की रक्त वाहिकाओं के विकास को प्रभावित कर सकती है, जिससे मस्तिष्क में रक्तस्राव या आँखों को नुकसान जैसी समस्याएँ हो सकती हैं। भविष्य में यह प्रोटीन मस्तिष्क विकास की समस्याओं के शुरुआती संकेत के रूप में काम कर सकता है और प्री-एक्लेम्पसिया जैसी गर्भावस्था की बीमारियों के इलाज का नया लक्ष्य भी बन सकता है।

Researchers at Virginia Tech's Fralin Biomedical Research Institute have identified a protein in the placenta that had not previously been found there and that plays a role in fetal blood-vessel development. The protein, soluble platelet-derived growth factor receptor beta (sR-beta), was described in a study published in the journal Angiogenesis. The team measured baseline levels of the protein in a healthy, developing placenta and found it is sensitive to oxygen. Researchers believe too much or too little of it could disrupt neurovascular development in the brain, potentially causing brain bleeds or eye damage from poor blood flow. Its first clinical use could be as a biomarker warning doctors of possible neurodevelopmental problems, and it may also become a therapeutic target for pregnancy disorders such as preeclampsia.

ورجینیا ٹیک کے محققین نے نال میں ایک ایسا پروٹین دریافت کیا ہے جو پہلے وہاں نہیں پایا گیا تھا۔ اس پروٹین کا نام سولوایبل پلیٹلیٹ ڈرائیوڈ گروتھ فیکٹر ریسیپٹر بیٹا (ایس آر بیٹا) ہے اور یہ بچے کی خون کی نالیوں کی نشوونما میں کردار ادا کرتا ہے۔ یہ تحقیق جریدے اینجیوجینیسس میں شائع ہوئی ہے۔ محققین کا کہنا ہے کہ یہ پروٹین آکسیجن کے لیے حساس ہے اور اس کی مقدار میں کمی بیشی بچے کے دماغ کی خون کی نالیوں کی نشوونما کو متاثر کر سکتی ہے، جس سے دماغی خون بہنا یا آنکھوں کو نقصان جیسے مسائل پیدا ہو سکتے ہیں۔ مستقبل میں یہ پروٹین دماغی نشوونما کے مسائل کی ابتدائی علامت کے طور پر کام کر سکتا ہے اور پری ایکلیمپسیا جیسی حمل کی بیماریوں کے علاج کا نیا ہدف بھی بن سکتا ہے۔

वर्जीनिया टेक के शोधकर्ताओं ने प्लेसेंटा में एक ऐसा प्रोटीन खोजा है जो पहले वहाँ नहीं पाया गया था। इस प्रोटीन का नाम सॉल्युबल प्लेटलेट-डेराइव्ड ग्रोथ फैक्टर रिसेप्टर बीटा (एसआर-बीटा) है और यह शिशु की रक्त वाहिकाओं के विकास में भूमिका निभाता है। यह शोध एंजियोजेनेसिस पत्रिका में प्रकाशित हुआ है। शोधकर्ताओं का कहना है कि यह प्रोटीन ऑक्सीजन के प्रति संवेदनशील है और इसकी मात्रा में कमी या अधिकता शिशु के मस्तिष्क की रक्त वाहिकाओं के विकास को प्रभावित कर सकती है, जिससे मस्तिष्क में रक्तस्राव या आँखों को नुकसान जैसी समस्याएँ हो सकती हैं। भविष्य में यह प्रोटीन मस्तिष्क विकास की समस्याओं के शुरुआती संकेत के रूप में काम कर सकता है और प्री-एक्लेम्पसिया जैसी गर्भावस्था की बीमारियों के इलाज का नया लक्ष्य भी बन सकता है।

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