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Global • 2026-10-29, 07:00 GMT • ~1 min read

Japan to begin first human trial of Nipah vaccine in April

جاپان اپریل میں نیپا وائرس کی ویکسین کا پہلا انسانی تجربہ شروع کرے گا

जापान अप्रैल में निपाह वायरस के टीके का पहला मानव परीक्षण शुरू करेगा

Japan to begin first human trial of Nipah vaccine in April

Key points

اہم نکات

मुख्य बातें

  • Researchers in Japan have announced the first human clinical trial of a vaccine against the deadly Nipah virus, set to begin in Belgium in April.
  • The candidate, developed at the University of Tokyo, inserts part of the Nipah virus's genetic information into a modified measles virus, prompting the immune system to produce antigen proteins similar to the virus's and strengthen the body's defences.
  • Nipah kills an estimated 40 to 75 percent of those infected, and there is currently no licensed vaccine or specific treatment.
  • جاپان کے محققین نے مہلک نیپا وائرس کے خلاف ویکسین کے پہلے انسانی کلینیکل ٹرائل کا اعلان کیا ہے، جو اپریل میں بیلجیئم میں شروع ہو گا۔ ٹوکیو یونیورسٹی میں تیار کردہ یہ امیدوار نیپا وائرس کی جینیاتی معلومات کا ایک حصہ تبدیل شدہ خسرہ وائرس میں داخل کرتا ہے، جس سے مدافعتی نظام وائرس جیسی اینٹیجن پروٹین بناتا ہے اور جسم کا دفاع مضبوط ہوتا ہے۔ نیپا سے متاثرہ افراد میں سے اندازاً 40 سے 75 فیصد ہلاک ہو جاتے ہیں، اور اس وقت اس کی کوئی منظور شدہ ویکسین یا مخصوص علاج موجود نہیں۔ ہیمسٹرز پر جانوروں کے تجربات میں حفاظت اور افادیت ثابت ہونے کے بعد فیز 1 ٹرائل میں 60 افراد شامل ہوں گے۔ الگ سے، آکسفورڈ یونیورسٹی کی ٹیم نے دسمبر میں بنگلہ دیش میں اپنے نیپا امیدوار کے فیز 2 ٹرائل شروع کیے ہیں۔
  • जापान के शोधकर्ताओं ने घातक निपाह वायरस के खिलाफ टीके के पहले मानव नैदानिक परीक्षण की घोषणा की है, जो अप्रैल में बेल्जियम में शुरू होगा। टोक्यो विश्वविद्यालय में विकसित यह उम्मीदवार निपाह वायरस की आनुवंशिक जानकारी का एक हिस्सा संशोधित खसरा वायरस में डालता है, जिससे प्रतिरक्षा तंत्र वायरस जैसे एंटीजन प्रोटीन बनाता है और शरीर की रक्षा मज़बूत होती है। निपाह से संक्रमित लोगों में से अनुमानित 40 से 75 प्रतिशत की मृत्यु हो जाती है, और वर्तमान में इसका कोई लाइसेंस प्राप्त टीका या विशिष्ट इलाज नहीं है। हैम्स्टर पर पशु परीक्षणों में सुरक्षा और प्रभावकारिता साबित होने के बाद पहले चरण के परीक्षण में 60 लोग शामिल होंगे। अलग से, ऑक्सफ़ोर्ड विश्वविद्यालय की टीम ने दिसंबर में बांग्लादेश में अपने निपाह उम्मीदवार के दूसरे चरण के परीक्षण शुरू किए हैं।

Researchers in Japan have announced the first human clinical trial of a vaccine against the deadly Nipah virus, set to begin in Belgium in April. The candidate, developed at the University of Tokyo, inserts part of the Nipah virus's genetic information into a modified measles virus, prompting the immune system to produce antigen proteins similar to the virus's and strengthen the body's defences. Nipah kills an estimated 40 to 75 percent of those infected, and there is currently no licensed vaccine or specific treatment. The Phase 1 trial will involve 60 subjects after animal trials in hamsters established safety and efficacy. Separately, an Oxford University team began Phase 2 trials of its own Nipah candidate in Bangladesh in December.

جاپان کے محققین نے مہلک نیپا وائرس کے خلاف ویکسین کے پہلے انسانی کلینیکل ٹرائل کا اعلان کیا ہے، جو اپریل میں بیلجیئم میں شروع ہو گا۔ ٹوکیو یونیورسٹی میں تیار کردہ یہ امیدوار نیپا وائرس کی جینیاتی معلومات کا ایک حصہ تبدیل شدہ خسرہ وائرس میں داخل کرتا ہے، جس سے مدافعتی نظام وائرس جیسی اینٹیجن پروٹین بناتا ہے اور جسم کا دفاع مضبوط ہوتا ہے۔ نیپا سے متاثرہ افراد میں سے اندازاً 40 سے 75 فیصد ہلاک ہو جاتے ہیں، اور اس وقت اس کی کوئی منظور شدہ ویکسین یا مخصوص علاج موجود نہیں۔ ہیمسٹرز پر جانوروں کے تجربات میں حفاظت اور افادیت ثابت ہونے کے بعد فیز 1 ٹرائل میں 60 افراد شامل ہوں گے۔ الگ سے، آکسفورڈ یونیورسٹی کی ٹیم نے دسمبر میں بنگلہ دیش میں اپنے نیپا امیدوار کے فیز 2 ٹرائل شروع کیے ہیں۔

जापान के शोधकर्ताओं ने घातक निपाह वायरस के खिलाफ टीके के पहले मानव नैदानिक परीक्षण की घोषणा की है, जो अप्रैल में बेल्जियम में शुरू होगा। टोक्यो विश्वविद्यालय में विकसित यह उम्मीदवार निपाह वायरस की आनुवंशिक जानकारी का एक हिस्सा संशोधित खसरा वायरस में डालता है, जिससे प्रतिरक्षा तंत्र वायरस जैसे एंटीजन प्रोटीन बनाता है और शरीर की रक्षा मज़बूत होती है। निपाह से संक्रमित लोगों में से अनुमानित 40 से 75 प्रतिशत की मृत्यु हो जाती है, और वर्तमान में इसका कोई लाइसेंस प्राप्त टीका या विशिष्ट इलाज नहीं है। हैम्स्टर पर पशु परीक्षणों में सुरक्षा और प्रभावकारिता साबित होने के बाद पहले चरण के परीक्षण में 60 लोग शामिल होंगे। अलग से, ऑक्सफ़ोर्ड विश्वविद्यालय की टीम ने दिसंबर में बांग्लादेश में अपने निपाह उम्मीदवार के दूसरे चरण के परीक्षण शुरू किए हैं।

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