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Global • 2026-11-02, 03:37 GMT • ~1 min read

Brain clears billions of faulty neurons around birth, Nature study finds

پیدائش کے وقت دماغ اربوں خراب نیورونز صاف کر دیتا ہے، نیچر کی تحقیق

जन्म के समय मस्तिष्क अरबों दोषपूर्ण न्यूरॉन्स को साफ कर देता है, नेचर अध्ययन

Brain clears billions of faulty neurons around birth, Nature study finds

Key points

اہم نکات

मुख्य बातें

  • An analysis of more than 2,300 nerve cells, published in Nature on 28 October, found more than a quarter of neurons in fetal brains had gained or lost parts of their chromosomes.
  • After birth only about 6 percent carried such faults, suggesting the developing brain removes most genetically damaged neurons around birth.
  • Researchers say this acts as quality control, keeping the neurons with the most intact genomes to build the brain's circuits.
  • 28 اکتوبر کو نیچر میں شائع ہونے والی تحقیق میں 2,300 سے زیادہ اعصابی خلیوں کا تجزیہ کیا گیا۔ معلوم ہوا کہ جنین کے دماغ میں ایک چوتھائی سے زیادہ نیورونز کے کروموسومز کے کچھ حصے بڑھ یا کم ہو گئے تھے، جبکہ پیدائش کے بعد صرف تقریباً 6 فیصد میں ایسی خرابیاں رہیں۔ محققین کا کہنا ہے کہ ترقی پذیر دماغ پیدائش کے وقت زیادہ تر جینیاتی طور پر خراب نیورونز کو ختم کر دیتا ہے، تاکہ سب سے محفوظ جینوم والے نیورونز دماغ کے سرکٹ بنائیں۔
  • 28 अक्टूबर को नेचर में प्रकाशित शोध में 2,300 से अधिक तंत्रिका कोशिकाओं का विश्लेषण किया गया। पता चला कि भ्रूण के मस्तिष्क में एक चौथाई से अधिक न्यूरॉन्स के गुणसूत्रों के कुछ हिस्से बढ़ या कम हो गए थे, जबकि जन्म के बाद केवल लगभग 6 प्रतिशत में ऐसी खराबियाँ रहीं। शोधकर्ताओं का कहना है कि विकसित हो रहा मस्तिष्क जन्म के समय अधिकतर आनुवंशिक रूप से खराब न्यूरॉन्स को हटा देता है, ताकि सबसे सुरक्षित जीनोम वाले न्यूरॉन्स मस्तिष्क के सर्किट बनाएँ।

An analysis of more than 2,300 nerve cells, published in Nature on 28 October, found more than a quarter of neurons in fetal brains had gained or lost parts of their chromosomes. After birth only about 6 percent carried such faults, suggesting the developing brain removes most genetically damaged neurons around birth. Researchers say this acts as quality control, keeping the neurons with the most intact genomes to build the brain's circuits.

28 اکتوبر کو نیچر میں شائع ہونے والی تحقیق میں 2,300 سے زیادہ اعصابی خلیوں کا تجزیہ کیا گیا۔ معلوم ہوا کہ جنین کے دماغ میں ایک چوتھائی سے زیادہ نیورونز کے کروموسومز کے کچھ حصے بڑھ یا کم ہو گئے تھے، جبکہ پیدائش کے بعد صرف تقریباً 6 فیصد میں ایسی خرابیاں رہیں۔ محققین کا کہنا ہے کہ ترقی پذیر دماغ پیدائش کے وقت زیادہ تر جینیاتی طور پر خراب نیورونز کو ختم کر دیتا ہے، تاکہ سب سے محفوظ جینوم والے نیورونز دماغ کے سرکٹ بنائیں۔

28 अक्टूबर को नेचर में प्रकाशित शोध में 2,300 से अधिक तंत्रिका कोशिकाओं का विश्लेषण किया गया। पता चला कि भ्रूण के मस्तिष्क में एक चौथाई से अधिक न्यूरॉन्स के गुणसूत्रों के कुछ हिस्से बढ़ या कम हो गए थे, जबकि जन्म के बाद केवल लगभग 6 प्रतिशत में ऐसी खराबियाँ रहीं। शोधकर्ताओं का कहना है कि विकसित हो रहा मस्तिष्क जन्म के समय अधिकतर आनुवंशिक रूप से खराब न्यूरॉन्स को हटा देता है, ताकि सबसे सुरक्षित जीनोम वाले न्यूरॉन्स मस्तिष्क के सर्किट बनाएँ।

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