Boston study finds new clues to aggressive colorectal cancer in younger patients

Boston study finds new clues to aggressive colorectal cancer in younger patients

Boston study finds new clues to aggressive colorectal cancer in younger patients

Researchers in Boston have found biological differences that may help explain why colorectal cancer can be more aggressive in younger patients. The team from Dana-Farber, Mass General Brigham and the Broad Institute studied 189 tumours, including 54 diagnosed before age 50, and published the work in Nature Medicine. Younger patients' tumours had a higher share of connective stromal cells and different gene activity, findings that could point towards future treatments, though the researchers caution the differences are not yet proven to cause the more aggressive disease.

Researchers in Boston have found biological differences that may help explain why colorectal cancer can be more aggressive in younger patients. The team from Dana-Farber, Mass General Brigham and the Broad Institute studied 189 tumours, including 54 diagnosed before age 50, and published the work in Nature Medicine. Younger patients' tumours had a higher share of connective stromal cells and different gene activity, findings that could point towards future treatments, though the researchers caution the differences are not yet proven to cause the more aggressive disease.

Researchers in Boston have found biological differences that may help explain why colorectal cancer can be more aggressive in younger patients. The team from Dana-Farber, Mass General Brigham and the Broad Institute studied 189 tumours, including 54 diagnosed before age 50, and published the work in Nature Medicine. Younger patients' tumours had a higher share of connective stromal cells and different gene activity, findings that could point towards future treatments, though the researchers caution the differences are not yet proven to cause the more aggressive disease.