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Global • 2026-11-01, 16:10 GMT • ~1 min read

Small study links gut treatment to behaviour and microbiome changes in autistic children

چھوٹی تحقیق میں آٹسٹک بچوں میں آنتوں کے علاج کا رویے اور مائیکرو بایوم سے تعلق ملا

छोटे अध्ययन में ऑटिस्टिक बच्चों में आंतों के उपचार का व्यवहार और माइक्रोबायोम से संबंध मिला

Small study links gut treatment to behaviour and microbiome changes in autistic children

Key points

اہم نکات

मुख्य बातें

  • A small pilot study published in Scientific Reports has explored whether an integrative treatment called TABAM can improve adaptive behaviour in children aged 3 to 7 with autism, alongside changes in gut bacteria and metabolites.
  • Sixteen of 22 enrolled children completed the 12-month study.
  • Adaptive behaviour scores improved within the TABAM group, but the change was not significantly different from conventional therapy, and gut bacteria diversity did not differ significantly between groups.
  • سائنٹیفک رپورٹس میں شائع ہونے والی ایک چھوٹی ابتدائی تحقیق میں دیکھا گیا ہے کہ آیا ٹیبیم نامی ایک مربوط علاج 3 سے 7 سال کے آٹسٹک بچوں میں موافقت پذیر رویے کو بہتر بنا سکتا ہے، ساتھ ہی آنتوں کے بیکٹیریا اور میٹابولائٹس میں تبدیلی بھی آتی ہے۔ 22 میں سے 16 بچوں نے 12 ماہ کی تحقیق مکمل کی۔ ٹیبیم گروپ میں موافقت پذیر رویے کے اسکور بہتر ہوئے، لیکن یہ تبدیلی روایتی علاج سے نمایاں طور پر مختلف نہیں تھی، اور آنتوں کے بیکٹیریا کی تنوع میں بھی گروپوں کے درمیان نمایاں فرق نہیں تھا۔ محققین نے کچھ تبدیلیاں پائیں، جن میں ٹیبیم گروپ میں فضلے میں سیروٹونن زیادہ اور بائیفیڈو بیکٹیریم زیادہ تھا، اور ان کا کہنا ہے کہ کسی فائدے کی تصدیق کے لیے بڑی تحقیق کی ضرورت ہے۔
  • साइंटिफिक रिपोर्ट्स में प्रकाशित एक छोटे पायलट अध्ययन में देखा गया है कि क्या टैबैम नामक एक समग्र उपचार 3 से 7 साल के ऑटिस्टिक बच्चों में अनुकूली व्यवहार को सुधार सकता है, साथ ही आंतों के बैक्टीरिया और मेटाबोलाइट्स में बदलाव भी आता है। 22 में से 16 बच्चों ने 12 महीने का अध्ययन पूरा किया। टैबैम समूह में अनुकूली व्यवहार के स्कोर सुधरे, लेकिन यह बदलाव पारंपरिक चिकित्सा से उल्लेखनीय रूप से अलग नहीं था, और आंतों के बैक्टीरिया की विविधता में भी समूहों के बीच उल्लेखनीय अंतर नहीं था। शोधकर्ताओं ने कुछ बदलाव पाए, जिनमें टैबैम समूह में मल में सेरोटोनिन अधिक और बिफिडोबैक्टीरियम अधिक था, और उनका कहना है कि किसी लाभ की पुष्टि के लिए बड़े अध्ययन की ज़रूरत है।

A small pilot study published in Scientific Reports has explored whether an integrative treatment called TABAM can improve adaptive behaviour in children aged 3 to 7 with autism, alongside changes in gut bacteria and metabolites. Sixteen of 22 enrolled children completed the 12-month study. Adaptive behaviour scores improved within the TABAM group, but the change was not significantly different from conventional therapy, and gut bacteria diversity did not differ significantly between groups. The researchers found some changes, including higher faecal serotonin and more Bifidobacterium in the TABAM group, and say larger studies are needed to confirm any benefit.

سائنٹیفک رپورٹس میں شائع ہونے والی ایک چھوٹی ابتدائی تحقیق میں دیکھا گیا ہے کہ آیا ٹیبیم نامی ایک مربوط علاج 3 سے 7 سال کے آٹسٹک بچوں میں موافقت پذیر رویے کو بہتر بنا سکتا ہے، ساتھ ہی آنتوں کے بیکٹیریا اور میٹابولائٹس میں تبدیلی بھی آتی ہے۔ 22 میں سے 16 بچوں نے 12 ماہ کی تحقیق مکمل کی۔ ٹیبیم گروپ میں موافقت پذیر رویے کے اسکور بہتر ہوئے، لیکن یہ تبدیلی روایتی علاج سے نمایاں طور پر مختلف نہیں تھی، اور آنتوں کے بیکٹیریا کی تنوع میں بھی گروپوں کے درمیان نمایاں فرق نہیں تھا۔ محققین نے کچھ تبدیلیاں پائیں، جن میں ٹیبیم گروپ میں فضلے میں سیروٹونن زیادہ اور بائیفیڈو بیکٹیریم زیادہ تھا، اور ان کا کہنا ہے کہ کسی فائدے کی تصدیق کے لیے بڑی تحقیق کی ضرورت ہے۔

साइंटिफिक रिपोर्ट्स में प्रकाशित एक छोटे पायलट अध्ययन में देखा गया है कि क्या टैबैम नामक एक समग्र उपचार 3 से 7 साल के ऑटिस्टिक बच्चों में अनुकूली व्यवहार को सुधार सकता है, साथ ही आंतों के बैक्टीरिया और मेटाबोलाइट्स में बदलाव भी आता है। 22 में से 16 बच्चों ने 12 महीने का अध्ययन पूरा किया। टैबैम समूह में अनुकूली व्यवहार के स्कोर सुधरे, लेकिन यह बदलाव पारंपरिक चिकित्सा से उल्लेखनीय रूप से अलग नहीं था, और आंतों के बैक्टीरिया की विविधता में भी समूहों के बीच उल्लेखनीय अंतर नहीं था। शोधकर्ताओं ने कुछ बदलाव पाए, जिनमें टैबैम समूह में मल में सेरोटोनिन अधिक और बिफिडोबैक्टीरियम अधिक था, और उनका कहना है कि किसी लाभ की पुष्टि के लिए बड़े अध्ययन की ज़रूरत है।

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