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Global • 2026-10-31, 05:10 GMT • ~1 min read

Space-grown brain tumour models could speed up cancer treatment research

خلا میں بنے دماغی رسولی کے ماڈل کینسر کے علاج کی تحقیق تیز کر سکتے ہیں

अंतरिक्ष में बने मस्तिष्क ट्यूमर मॉडल कैंसर इलाज अनुसंधान तेज कर सकते हैं

Space-grown brain tumour models could speed up cancer treatment research

Key points

اہم نکات

मुख्य बातें

  • Researchers at the University of Notre Dame grew three-dimensional models of glioblastoma, the most common malignant primary brain tumour in adults, aboard the International Space Station, and found they mimic real tumours better than models grown on Earth.
  • In the space-grown organoids, genes linked to inflammation, immune response and blood vessel growth were more active, and proteins linked to more aggressive disease were higher.
  • The team says the models, described in the journal PNAS, could help test new treatments for one of the deadliest cancers.
  • یونیورسٹی آف نوٹر ڈیم کے محققین نے بین الاقوامی خلائی اسٹیشن پر گلیوبلاسٹوما کے سہ جہتی ماڈل بنائے، جو بالغوں میں دماغ کی سب سے عام مہلک رسولی ہے، اور پایا کہ یہ زمین پر بنے ماڈلوں کے مقابلے میں اصلی رسولی کی زیادہ بہتر نقل کرتے ہیں۔ خلا میں بنے ان ماڈلوں میں سوزش، مدافعتی ردعمل اور خون کی نالیوں کی افزائش سے جڑے جین زیادہ سرگرم تھے، اور زیادہ خطرناک بیماری سے جڑے پروٹین بھی زیادہ تھے۔ ٹیم کا کہنا ہے کہ یہ ماڈل، جن کی تفصیل جریدے پی این اے ایس میں شائع ہوئی ہے، اس جان لیوا کینسر کے نئے علاج جانچنے میں مدد کر سکتے ہیں۔
  • नोट्रे डेम विश्वविद्यालय के शोधकर्ताओं ने अंतरराष्ट्रीय अंतरिक्ष स्टेशन पर ग्लियोब्लास्टोमा के त्रि-आयामी मॉडल बनाए, जो वयस्कों में मस्तिष्क का सबसे आम घातक ट्यूमर है, और पाया कि ये पृथ्वी पर बने मॉडलों की तुलना में असली ट्यूमर की बेहतर नकल करते हैं। अंतरिक्ष में बने इन मॉडलों में सूजन, प्रतिरक्षा प्रतिक्रिया और रक्त वाहिकाओं के विकास से जुड़े जीन अधिक सक्रिय थे, और अधिक आक्रामक बीमारी से जुड़े प्रोटीन भी अधिक थे। टीम का कहना है कि ये मॉडल, जिनका विवरण पीएनएएस पत्रिका में प्रकाशित हुआ है, इस जानलेवा कैंसर के नए इलाज परखने में मदद कर सकते हैं।

Researchers at the University of Notre Dame grew three-dimensional models of glioblastoma, the most common malignant primary brain tumour in adults, aboard the International Space Station, and found they mimic real tumours better than models grown on Earth. In the space-grown organoids, genes linked to inflammation, immune response and blood vessel growth were more active, and proteins linked to more aggressive disease were higher. The team says the models, described in the journal PNAS, could help test new treatments for one of the deadliest cancers.

یونیورسٹی آف نوٹر ڈیم کے محققین نے بین الاقوامی خلائی اسٹیشن پر گلیوبلاسٹوما کے سہ جہتی ماڈل بنائے، جو بالغوں میں دماغ کی سب سے عام مہلک رسولی ہے، اور پایا کہ یہ زمین پر بنے ماڈلوں کے مقابلے میں اصلی رسولی کی زیادہ بہتر نقل کرتے ہیں۔ خلا میں بنے ان ماڈلوں میں سوزش، مدافعتی ردعمل اور خون کی نالیوں کی افزائش سے جڑے جین زیادہ سرگرم تھے، اور زیادہ خطرناک بیماری سے جڑے پروٹین بھی زیادہ تھے۔ ٹیم کا کہنا ہے کہ یہ ماڈل، جن کی تفصیل جریدے پی این اے ایس میں شائع ہوئی ہے، اس جان لیوا کینسر کے نئے علاج جانچنے میں مدد کر سکتے ہیں۔

नोट्रे डेम विश्वविद्यालय के शोधकर्ताओं ने अंतरराष्ट्रीय अंतरिक्ष स्टेशन पर ग्लियोब्लास्टोमा के त्रि-आयामी मॉडल बनाए, जो वयस्कों में मस्तिष्क का सबसे आम घातक ट्यूमर है, और पाया कि ये पृथ्वी पर बने मॉडलों की तुलना में असली ट्यूमर की बेहतर नकल करते हैं। अंतरिक्ष में बने इन मॉडलों में सूजन, प्रतिरक्षा प्रतिक्रिया और रक्त वाहिकाओं के विकास से जुड़े जीन अधिक सक्रिय थे, और अधिक आक्रामक बीमारी से जुड़े प्रोटीन भी अधिक थे। टीम का कहना है कि ये मॉडल, जिनका विवरण पीएनएएस पत्रिका में प्रकाशित हुआ है, इस जानलेवा कैंसर के नए इलाज परखने में मदद कर सकते हैं।

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