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Global • 2026-10-31, 13:47 GMT • ~1 min read

Scientists rewrite human DNA inside the body for the first time

سائنسدانوں نے پہلی بار جسم کے اندر انسانی ڈی این اے کو دوبارہ لکھا

वैज्ञानिकों ने पहली बार शरीर के अंदर मानव डीएनए को फिर से लिखा

Scientists rewrite human DNA inside the body for the first time

Key points

اہم نکات

मुख्य बातें

  • Scientists have rewritten a person's DNA directly inside the body for the first time, in a clinical trial for Wilson's disease, a rare genetic condition that causes copper to build up in the body.
  • The treatment, announced by Massachusetts-based biotechnology company Prime Medicine, uses a technique called prime editing, which can rewrite DNA more precisely than standard CRISPR methods.
  • The trial will assess the treatment's safety and whether it helps patients, and the company expects to announce the first results in 2027.
  • سائنسدانوں نے پہلی بار جسم کے اندر ہی ایک شخص کے ڈی این اے کو دوبارہ لکھا ہے، یہ ولسن بیماری کے کلینیکل ٹرائل میں ہوا ہے، جو ایک نایاب جینیاتی بیماری ہے جس میں جسم میں تانبا جمع ہو جاتا ہے۔ یہ علاج میساچوسٹس کی بایوٹیکنالوجی کمپنی پرائم میڈیسن نے اعلان کیا ہے، اور اس میں پرائم ایڈیٹنگ نامی تکنیک استعمال ہوتی ہے جو عام کرسپر طریقوں سے زیادہ درستگی سے ڈی این اے بدل سکتی ہے۔ ٹرائل میں علاج کی حفاظت اور مریضوں پر اس کے فائدے کو جانچا جائے گا، اور کمپنی 2027 میں پہلے نتائج کا اعلان کرنے کی توقع رکھتی ہے۔ یہ ابھی ابتدائی قدم ہے، ثابت شدہ علاج نہیں، لیکن محققین اسے جین ایڈیٹنگ طب میں ایک سنگ میل سمجھتے ہیں۔
  • वैज्ञानिकों ने पहली बार शरीर के अंदर ही एक व्यक्ति के डीएनए को फिर से लिखा है, यह विल्सन रोग के क्लिनिकल परीक्षण में हुआ है, जो एक दुर्लभ आनुवंशिक बीमारी है जिसमें शरीर में ताँबा जमा हो जाता है। यह इलाज मैसाचुसेट्स की बायोटेक कंपनी प्राइम मेडिसिन ने घोषित किया है, और इसमें प्राइम एडिटिंग नामक तकनीक का इस्तेमाल होता है जो सामान्य क्रिस्पर तरीकों से ज़्यादा सटीकता से डीएनए बदल सकती है। परीक्षण में इलाज की सुरक्षा और मरीज़ों पर इसके लाभ को जाँचा जाएगा, और कंपनी 2027 में पहले नतीजे घोषित करने की उम्मीद रखती है। यह अभी शुरुआती कदम है, सिद्ध इलाज नहीं, लेकिन शोधकर्ता इसे जीन-संपादन चिकित्सा में एक मील का पत्थर मानते हैं।

Scientists have rewritten a person's DNA directly inside the body for the first time, in a clinical trial for Wilson's disease, a rare genetic condition that causes copper to build up in the body. The treatment, announced by Massachusetts-based biotechnology company Prime Medicine, uses a technique called prime editing, which can rewrite DNA more precisely than standard CRISPR methods. The trial will assess the treatment's safety and whether it helps patients, and the company expects to announce the first results in 2027. It is an early step, not yet a proven cure, but researchers see it as a milestone for gene-editing medicine.

سائنسدانوں نے پہلی بار جسم کے اندر ہی ایک شخص کے ڈی این اے کو دوبارہ لکھا ہے، یہ ولسن بیماری کے کلینیکل ٹرائل میں ہوا ہے، جو ایک نایاب جینیاتی بیماری ہے جس میں جسم میں تانبا جمع ہو جاتا ہے۔ یہ علاج میساچوسٹس کی بایوٹیکنالوجی کمپنی پرائم میڈیسن نے اعلان کیا ہے، اور اس میں پرائم ایڈیٹنگ نامی تکنیک استعمال ہوتی ہے جو عام کرسپر طریقوں سے زیادہ درستگی سے ڈی این اے بدل سکتی ہے۔ ٹرائل میں علاج کی حفاظت اور مریضوں پر اس کے فائدے کو جانچا جائے گا، اور کمپنی 2027 میں پہلے نتائج کا اعلان کرنے کی توقع رکھتی ہے۔ یہ ابھی ابتدائی قدم ہے، ثابت شدہ علاج نہیں، لیکن محققین اسے جین ایڈیٹنگ طب میں ایک سنگ میل سمجھتے ہیں۔

वैज्ञानिकों ने पहली बार शरीर के अंदर ही एक व्यक्ति के डीएनए को फिर से लिखा है, यह विल्सन रोग के क्लिनिकल परीक्षण में हुआ है, जो एक दुर्लभ आनुवंशिक बीमारी है जिसमें शरीर में ताँबा जमा हो जाता है। यह इलाज मैसाचुसेट्स की बायोटेक कंपनी प्राइम मेडिसिन ने घोषित किया है, और इसमें प्राइम एडिटिंग नामक तकनीक का इस्तेमाल होता है जो सामान्य क्रिस्पर तरीकों से ज़्यादा सटीकता से डीएनए बदल सकती है। परीक्षण में इलाज की सुरक्षा और मरीज़ों पर इसके लाभ को जाँचा जाएगा, और कंपनी 2027 में पहले नतीजे घोषित करने की उम्मीद रखती है। यह अभी शुरुआती कदम है, सिद्ध इलाज नहीं, लेकिन शोधकर्ता इसे जीन-संपादन चिकित्सा में एक मील का पत्थर मानते हैं।

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