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pitch to voters on Election DayDisney expected to lay off thousands in its biggest round of cuts this yearDisney expected to lay off thousands in its biggest round of cuts this yearDisney expected to lay off thousands in its biggest round of cuts this yearAckman warns speculative trading is turning the stock market into a casinoAckman warns speculative trading is turning the stock market into a casinoAckman warns speculative trading is turning the stock market into a casinoRedMagic takes its RGB liquid-cooled gaming phone global as the 12 ProRedMagic takes its RGB liquid-cooled gaming phone global as the 12 ProRedMagic takes its RGB liquid-cooled gaming phone global as the 12 ProMalachi Jordan commits to St. John's, its first five-star recruit in 13 yearsMalachi Jordan commits to St. John's, its first five-star recruit in 13 yearsMalachi Jordan commits to St. John's, its first five-star recruit in 13 yearsSigns point to a big BioWare N7 Day celebration planned before the studio closedSigns point to a big BioWare N7 Day celebration planned before the studio closedSigns point to a big BioWare N7 Day celebration planned before the studio closedCritics of Ilhan Omar describe threats and intimidation, report saysCritics of Ilhan Omar describe threats and intimidation, report saysCritics of Ilhan Omar describe threats and intimidation, report saysGoogle app may replace its bottom bar tabs with Videos, Images and YouGoogle app may replace its bottom bar tabs with Videos, Images and YouGoogle app may replace its bottom bar tabs with Videos, Images and YouStar Wars Jedi: Survivor's final hidden secret found after three and a half yearsStar Wars Jedi: Survivor's final hidden secret found after three and a half yearsStar Wars Jedi: Survivor's final hidden secret found after three and a half yearsWar widens in the Black Sea, testing NATO's red linesWar widens in the Black Sea, testing NATO's red linesWar widens in the Black Sea, testing NATO's red linesGoogle confirms Android Family Hub, a new family space inside SettingsGoogle confirms Android Family Hub, a new family space inside SettingsGoogle confirms Android Family Hub, a new family space inside SettingsFive rescued off Kiribati after three months adrift at sea, four still missingFive rescued off Kiribati after three months adrift at sea, four still missingFive rescued off Kiribati after three months adrift at sea, four still missingDeath toll reaches 31 after Russian strikes hit a Ukrainian aid siteDeath toll reaches 31 after Russian strikes hit a Ukrainian aid siteDeath toll reaches 31 after Russian strikes hit a Ukrainian aid siteKing calls the slave trade a shameful chapter in Commonwealth addressKing calls the slave trade a shameful chapter in Commonwealth addressKing calls the slave trade a shameful chapter in Commonwealth addressScientists spot a potentially massive dwarf planet candidate beyond PlutoScientists spot a potentially massive dwarf planet candidate beyond PlutoScientists spot a potentially massive dwarf planet candidate beyond PlutoEating blueberries every day may ease depressive symptoms in older adultsEating blueberries every day may ease depressive symptoms in older adultsEating blueberries every day may ease depressive symptoms in older adultsIran warns of a 'new battlefield' after reported US strike on QeshmIran warns of a 'new battlefield' after reported US strike on QeshmIran warns of a 'new battlefield' after reported US strike on Qeshm
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USA • 2026-11-02, 04:45 ET • ~1 min read

Common diabetes drugs may trigger side effects that need more drugs, study finds

عام ذیابیطس کی دوائیں مضر اثرات پیدا کر سکتی ہیں جن کے لیے مزید دوائیں درکار ہوں، تحقیق

आम मधुमेह की दवाएँ ऐसे दुष्प्रभाव पैदा कर सकती हैं जिनके लिए और दवाएँ चाहिए, अध्ययन

Common diabetes drugs may trigger side effects that need more drugs, study finds

Key points

اہم نکات

मुख्य बातें

  • A study published in BMC Medicine has found that common type 2 diabetes medicines can set off 'prescribing cascades', where a side effect is treated with yet another drug.
  • Researchers analysed two large healthcare databases covering more than 387,000 people and found seven potential cascades among 12 medicine pairings examined.
  • SGLT2 inhibitors were often followed by antibiotics for urinary infections, antifungals and bladder medicines, while thiazolidinediones were often followed by water pills for swelling.
  • بی ایم سی میڈیسن میں شائع ہونے والی ایک تحقیق میں پایا گیا ہے کہ ٹائپ 2 ذیابیطس کی عام دوائیں 'پریسکرائبنگ کیسکیڈ' پیدا کر سکتی ہیں، یعنی ایک دوا کے مضر اثر کا علاج ایک اور دوا سے کیا جاتا ہے۔ محققین نے 387,000 سے زیادہ افراد پر مشتمل دو بڑے صحت کے ڈیٹا بیس کا جائزہ لیا اور 12 دواؤں کے جوڑوں میں سات ممکنہ کیسکیڈ پائے۔ ایس جی ایل ٹی 2 انہیبیٹرز کے بعد اکثر پیشاب کی انفیکشن کے لیے اینٹی بایوٹکس، اینٹی فنگل اور مثانے کی دوائیں دی گئیں، جبکہ تھایا زولیڈین ڈائیونز کے بعد سوجن کے لیے واٹر پلز دی گئیں۔ محققین نے کہا کہ مضر اثر کو جلد پہچاننے سے ڈاکٹر ایک اور دوا شامل کرنے کے بجائے پہلی دوا بند یا تبدیل کر سکتے ہیں۔
  • बीएमसी मेडिसिन में प्रकाशित एक अध्ययन में पाया गया है कि टाइप 2 मधुमेह की आम दवाएँ 'प्रिस्क्राइबिंग कैस्केड' पैदा कर सकती हैं, यानी एक दवा के दुष्प्रभाव का इलाज एक और दवा से किया जाता है। शोधकर्ताओं ने 3,87,000 से अधिक लोगों वाले दो बड़े स्वास्थ्य डेटाबेस का विश्लेषण किया और 12 दवा जोड़ों में सात संभावित कैस्केड पाए। एसजीएलटी2 इनहिबिटर के बाद अक्सर मूत्र संक्रमण के लिए एंटीबायोटिक्स, एंटीफंगल और मूत्राशय की दवाएँ दी गईं, जबकि थियाज़ोलिडीनडायोन के बाद सूजन के लिए वॉटर पिल्स दी गईं। शोधकर्ताओं ने कहा कि दुष्प्रभाव को जल्दी पहचानने से डॉक्टर एक और दवा जोड़ने के बजाय पहली दवा बंद या बदल सकते हैं।

A study published in BMC Medicine has found that common type 2 diabetes medicines can set off 'prescribing cascades', where a side effect is treated with yet another drug. Researchers analysed two large healthcare databases covering more than 387,000 people and found seven potential cascades among 12 medicine pairings examined. SGLT2 inhibitors were often followed by antibiotics for urinary infections, antifungals and bladder medicines, while thiazolidinediones were often followed by water pills for swelling. The researchers said recognising a side effect early could allow doctors to stop or change the first medicine instead of adding another one.

بی ایم سی میڈیسن میں شائع ہونے والی ایک تحقیق میں پایا گیا ہے کہ ٹائپ 2 ذیابیطس کی عام دوائیں 'پریسکرائبنگ کیسکیڈ' پیدا کر سکتی ہیں، یعنی ایک دوا کے مضر اثر کا علاج ایک اور دوا سے کیا جاتا ہے۔ محققین نے 387,000 سے زیادہ افراد پر مشتمل دو بڑے صحت کے ڈیٹا بیس کا جائزہ لیا اور 12 دواؤں کے جوڑوں میں سات ممکنہ کیسکیڈ پائے۔ ایس جی ایل ٹی 2 انہیبیٹرز کے بعد اکثر پیشاب کی انفیکشن کے لیے اینٹی بایوٹکس، اینٹی فنگل اور مثانے کی دوائیں دی گئیں، جبکہ تھایا زولیڈین ڈائیونز کے بعد سوجن کے لیے واٹر پلز دی گئیں۔ محققین نے کہا کہ مضر اثر کو جلد پہچاننے سے ڈاکٹر ایک اور دوا شامل کرنے کے بجائے پہلی دوا بند یا تبدیل کر سکتے ہیں۔

बीएमसी मेडिसिन में प्रकाशित एक अध्ययन में पाया गया है कि टाइप 2 मधुमेह की आम दवाएँ 'प्रिस्क्राइबिंग कैस्केड' पैदा कर सकती हैं, यानी एक दवा के दुष्प्रभाव का इलाज एक और दवा से किया जाता है। शोधकर्ताओं ने 3,87,000 से अधिक लोगों वाले दो बड़े स्वास्थ्य डेटाबेस का विश्लेषण किया और 12 दवा जोड़ों में सात संभावित कैस्केड पाए। एसजीएलटी2 इनहिबिटर के बाद अक्सर मूत्र संक्रमण के लिए एंटीबायोटिक्स, एंटीफंगल और मूत्राशय की दवाएँ दी गईं, जबकि थियाज़ोलिडीनडायोन के बाद सूजन के लिए वॉटर पिल्स दी गईं। शोधकर्ताओं ने कहा कि दुष्प्रभाव को जल्दी पहचानने से डॉक्टर एक और दवा जोड़ने के बजाय पहली दवा बंद या बदल सकते हैं।

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