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depressive symptoms in older adultsIran warns of a 'new battlefield' after reported US strike on QeshmIran warns of a 'new battlefield' after reported US strike on QeshmIran warns of a 'new battlefield' after reported US strike on QeshmAnthropic's compute costs eat a bigger share of revenue as growth surgesAnthropic's compute costs eat a bigger share of revenue as growth surgesAnthropic's compute costs eat a bigger share of revenue as growth surgesStartup plans 50,000 space mirrors to beam sunlight down at nightStartup plans 50,000 space mirrors to beam sunlight down at nightStartup plans 50,000 space mirrors to beam sunlight down at nightChina steps up Middle East diplomacy as fears grow of a renewed US-Iran warChina steps up Middle East diplomacy as fears grow of a renewed US-Iran warChina steps up Middle East diplomacy as fears grow of a renewed US-Iran warTrump makes his last pitch to voters on Election DayTrump makes his last pitch to voters on Election DayTrump makes his last pitch to voters on Election DayDisney expected to lay off thousands in its biggest round of cuts this yearDisney expected to lay off thousands in its biggest round of cuts this yearDisney expected to lay off thousands in its biggest round of cuts this yearAckman warns speculative trading is turning the stock market into a casinoAckman warns speculative trading is turning the stock market into a casinoAckman warns speculative trading is turning the stock market into a casinoRedMagic takes its RGB liquid-cooled gaming phone global as the 12 ProRedMagic takes its RGB liquid-cooled gaming phone global as the 12 ProRedMagic takes its RGB liquid-cooled gaming phone global as the 12 ProMalachi Jordan commits to St. John's, its first five-star recruit in 13 yearsMalachi Jordan commits to St. John's, its first five-star recruit in 13 yearsMalachi Jordan commits to St. John's, its first five-star recruit in 13 yearsSigns point to a big BioWare N7 Day celebration planned before the studio closedSigns point to a big BioWare N7 Day celebration planned before the studio closedSigns point to a big BioWare N7 Day celebration planned before the studio closedCritics of Ilhan Omar describe threats and intimidation, report saysCritics of Ilhan Omar describe threats and intimidation, report saysCritics of Ilhan Omar describe threats and intimidation, report saysGoogle app may replace its bottom bar tabs with Videos, Images and YouGoogle app may replace its bottom bar tabs with Videos, Images and YouGoogle app may replace its bottom bar tabs with Videos, Images and YouStar Wars Jedi: Survivor's final hidden secret found after three and a half yearsStar Wars Jedi: Survivor's final hidden secret found after three and a half yearsStar Wars Jedi: Survivor's final hidden secret found after three and a half yearsWar widens in the Black Sea, testing NATO's red linesWar widens in the Black Sea, testing NATO's red linesWar widens in the Black Sea, testing NATO's red linesGoogle confirms Android Family Hub, a new family space inside SettingsGoogle confirms Android Family Hub, a new family space inside SettingsGoogle confirms Android Family Hub, a new family space inside SettingsFive rescued off Kiribati after three months adrift at sea, four still missingFive rescued off Kiribati after three months adrift at sea, four still missingFive rescued off Kiribati after three months adrift at sea, four still missingDeath toll reaches 31 after Russian strikes hit a Ukrainian aid siteDeath toll reaches 31 after Russian strikes hit a Ukrainian aid siteDeath toll reaches 31 after Russian strikes hit a Ukrainian aid siteKing calls the slave trade a shameful chapter in Commonwealth addressKing calls the slave trade a shameful chapter in Commonwealth addressKing calls the slave trade a shameful chapter in Commonwealth addressScientists spot a potentially massive dwarf planet candidate beyond PlutoScientists spot a potentially massive dwarf planet candidate beyond PlutoScientists spot a potentially massive dwarf planet candidate beyond PlutoEating blueberries every day may ease depressive symptoms in older adultsEating blueberries every day may ease depressive symptoms in older adultsEating blueberries every day may ease depressive symptoms in older adultsIran warns of a 'new battlefield' after reported US strike on QeshmIran warns of a 'new battlefield' after reported US strike on QeshmIran warns of a 'new battlefield' after reported US strike on Qeshm
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USA • 2026-11-02, 01:45 ET • ~1 min read

Blood test could flag Alzheimer's risk up to 10 years early

خون کا ٹیسٹ الزائمر کے خطرے کی 10 سال پہلے نشاندہی کر سکتا ہے

रक्त परीक्षण अल्जाइमर के जोखिम की 10 साल पहले पहचान कर सकता है

Blood test could flag Alzheimer's risk up to 10 years early

Key points

اہم نکات

मुख्य बातें

  • A simple blood test measuring the biomarker p-tau217 could help identify older adults at higher risk of Alzheimer's-related memory problems years before symptoms appear, an international study of 2,684 people with no cognitive impairment found.
  • Those with very high levels faced an estimated 38% chance of cognitive impairment within five years and 78% within 10 years, though the longer estimate rested on less data.
  • Led by Mass General Brigham and published in JAMA, the work still cautions that the test is not recommended as routine screening for healthy people, as no disease-modifying treatment exists for this early stage.
  • بائیو مارکر پی-ٹاؤ 217 کی پیمائش کرنے والا ایک سادہ خون کا ٹیسٹ ان بزرگوں کی نشاندہی میں مدد کر سکتا ہے جنہیں علامات ظاہر ہونے سے کئی سال پہلے الزائمر سے متعلق یادداشت کے مسائل کا زیادہ خطرہ ہو، 2,684 افراد پر ہونے والی بین الاقوامی تحقیق میں یہ بات سامنے آئی ہے۔ بہت زیادہ سطح والے افراد میں پانچ سال میں 38 فیصد اور دس سال میں 78 فیصد امکان پایا گیا، اگرچہ طویل تخمینہ کم ڈیٹا پر مبنی تھا۔ ماس جنرل بریگھم کی قیادت میں یہ تحقیق JAMA میں شائع ہوئی، لیکن ماہرین خبردار کرتے ہیں کہ صحت مند لوگوں کے لیے یہ ٹیسٹ معمول کی جانچ کے طور پر تجویز نہیں کیا جاتا، کیونکہ اس ابتدائی مرحلے کا کوئی بیماری بدلنے والا علاج نہیں ہے۔
  • बायोमार्कर पी-टाऊ 217 को मापने वाला एक साधारण रक्त परीक्षण उन बुजुर्गों की पहचान में मदद कर सकता है जिन्हें लक्षण दिखने से कई साल पहले अल्जाइमर से जुड़ी याददाश्त की समस्याओं का अधिक जोखिम हो, 2,684 लोगों पर हुए अंतरराष्ट्रीय अध्ययन में यह बात सामने आई है। बहुत अधिक स्तर वाले लोगों में पांच साल में 38% और दस साल में 78% संभावना पाई गई, हालांकि लंबा अनुमान कम आंकड़ों पर आधारित था। मास जनरल ब्रिघम के नेतृत्व में यह शोध JAMA में प्रकाशित हुआ, लेकिन विशेषज्ञ चेतावनी देते हैं कि स्वस्थ लोगों के लिए यह परीक्षण नियमित जांच के रूप में अनुशंसित नहीं है, क्योंकि इस शुरुआती चरण का कोई रोग-परिवर्तक उपचार नहीं है।

A simple blood test measuring the biomarker p-tau217 could help identify older adults at higher risk of Alzheimer's-related memory problems years before symptoms appear, an international study of 2,684 people with no cognitive impairment found. Those with very high levels faced an estimated 38% chance of cognitive impairment within five years and 78% within 10 years, though the longer estimate rested on less data. Led by Mass General Brigham and published in JAMA, the work still cautions that the test is not recommended as routine screening for healthy people, as no disease-modifying treatment exists for this early stage.

بائیو مارکر پی-ٹاؤ 217 کی پیمائش کرنے والا ایک سادہ خون کا ٹیسٹ ان بزرگوں کی نشاندہی میں مدد کر سکتا ہے جنہیں علامات ظاہر ہونے سے کئی سال پہلے الزائمر سے متعلق یادداشت کے مسائل کا زیادہ خطرہ ہو، 2,684 افراد پر ہونے والی بین الاقوامی تحقیق میں یہ بات سامنے آئی ہے۔ بہت زیادہ سطح والے افراد میں پانچ سال میں 38 فیصد اور دس سال میں 78 فیصد امکان پایا گیا، اگرچہ طویل تخمینہ کم ڈیٹا پر مبنی تھا۔ ماس جنرل بریگھم کی قیادت میں یہ تحقیق JAMA میں شائع ہوئی، لیکن ماہرین خبردار کرتے ہیں کہ صحت مند لوگوں کے لیے یہ ٹیسٹ معمول کی جانچ کے طور پر تجویز نہیں کیا جاتا، کیونکہ اس ابتدائی مرحلے کا کوئی بیماری بدلنے والا علاج نہیں ہے۔

बायोमार्कर पी-टाऊ 217 को मापने वाला एक साधारण रक्त परीक्षण उन बुजुर्गों की पहचान में मदद कर सकता है जिन्हें लक्षण दिखने से कई साल पहले अल्जाइमर से जुड़ी याददाश्त की समस्याओं का अधिक जोखिम हो, 2,684 लोगों पर हुए अंतरराष्ट्रीय अध्ययन में यह बात सामने आई है। बहुत अधिक स्तर वाले लोगों में पांच साल में 38% और दस साल में 78% संभावना पाई गई, हालांकि लंबा अनुमान कम आंकड़ों पर आधारित था। मास जनरल ब्रिघम के नेतृत्व में यह शोध JAMA में प्रकाशित हुआ, लेकिन विशेषज्ञ चेतावनी देते हैं कि स्वस्थ लोगों के लिए यह परीक्षण नियमित जांच के रूप में अनुशंसित नहीं है, क्योंकि इस शुरुआती चरण का कोई रोग-परिवर्तक उपचार नहीं है।

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