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Global • 2026-10-28, 13:53 GMT • ~1 min read

Alzheimer's drug trial reaches database lock, results due mid-November

الزائمر دوا کا ٹرائل آخری مرحلے میں، نتائج نومبر کے وسط میں آئیں گے

अल्जाइमर दवा का परीक्षण अंतिम चरण में, परिणाम नवंबर के मध्य में आएंगे

Alzheimer's drug trial reaches database lock, results due mid-November

Key points

اہم نکات

मुख्य बातें

  • Actinogen Medical has reached database lock in its pivotal XanaMIA trial of oral Xanamem for Alzheimer's disease, and narrowed its guidance for final topline results to mid-November.
  • The trial tested Xanamem 10 mg against a placebo over 36 weeks in 247 participants across Australia and the United States, selected through a blood test for elevated pTau181, a marker linked to Alzheimer's.
  • The drug works by controlling cortisol in the brain, and the company says it could become a transformational treatment option for patients and their families if the results are positive.
  • ایکٹینوجن میڈیکل نے الزائمر کی بیماری کے لیے زبانی دوا زینامیم کے اہم ٹرائل زینا ایم آئی اے میں ڈیٹا بیس لاک مکمل کر لیا ہے، اور حتمی نتائج نومبر کے وسط میں آنے کی توقع ہے۔ اس ٹرائل میں آسٹریلیا اور امریکہ کے 247 مریضوں پر 36 ہفتوں تک زینامیم 10 ملی گرام کا پلیسبو سے موازنہ کیا گیا، جن کا انتخاب خون کے ٹیسٹ سے کیا گیا تھا۔ یہ دوا دماغ میں کورٹیسول کو کنٹرول کر کے کام کرتی ہے، اور کمپنی کا کہنا ہے کہ اگر نتائج مثبت رہے تو یہ مریضوں اور ان کے خاندانوں کے لیے ایک اہم علاج ثابت ہو سکتی ہے۔
  • एक्टिनोजेन मेडिकल ने अल्जाइमर रोग के लिए मौखिक दवा ज़ैनामेम के महत्वपूर्ण परीक्षण ज़ैना एमआईए में डेटाबेस लॉक पूरा कर लिया है, और अंतिम परिणाम नवंबर के मध्य में आने की उम्मीद है। इस परीक्षण में ऑस्ट्रेलिया और अमेरिका के 247 मरीजों पर 36 हफ्तों तक ज़ैनामेम 10 मिलीग्राम की तुलना प्लेसीबो से की गई, जिनका चयन रक्त परीक्षण से किया गया था। यह दवा मस्तिष्क में कोर्टिसोल को नियंत्रित करके काम करती है, और कंपनी का कहना है कि यदि परिणाम सकारात्मक रहे तो यह मरीजों और उनके परिवारों के लिए एक महत्वपूर्ण उपचार साबित हो सकती है।

Actinogen Medical has reached database lock in its pivotal XanaMIA trial of oral Xanamem for Alzheimer's disease, and narrowed its guidance for final topline results to mid-November. The trial tested Xanamem 10 mg against a placebo over 36 weeks in 247 participants across Australia and the United States, selected through a blood test for elevated pTau181, a marker linked to Alzheimer's. The drug works by controlling cortisol in the brain, and the company says it could become a transformational treatment option for patients and their families if the results are positive.

ایکٹینوجن میڈیکل نے الزائمر کی بیماری کے لیے زبانی دوا زینامیم کے اہم ٹرائل زینا ایم آئی اے میں ڈیٹا بیس لاک مکمل کر لیا ہے، اور حتمی نتائج نومبر کے وسط میں آنے کی توقع ہے۔ اس ٹرائل میں آسٹریلیا اور امریکہ کے 247 مریضوں پر 36 ہفتوں تک زینامیم 10 ملی گرام کا پلیسبو سے موازنہ کیا گیا، جن کا انتخاب خون کے ٹیسٹ سے کیا گیا تھا۔ یہ دوا دماغ میں کورٹیسول کو کنٹرول کر کے کام کرتی ہے، اور کمپنی کا کہنا ہے کہ اگر نتائج مثبت رہے تو یہ مریضوں اور ان کے خاندانوں کے لیے ایک اہم علاج ثابت ہو سکتی ہے۔

एक्टिनोजेन मेडिकल ने अल्जाइमर रोग के लिए मौखिक दवा ज़ैनामेम के महत्वपूर्ण परीक्षण ज़ैना एमआईए में डेटाबेस लॉक पूरा कर लिया है, और अंतिम परिणाम नवंबर के मध्य में आने की उम्मीद है। इस परीक्षण में ऑस्ट्रेलिया और अमेरिका के 247 मरीजों पर 36 हफ्तों तक ज़ैनामेम 10 मिलीग्राम की तुलना प्लेसीबो से की गई, जिनका चयन रक्त परीक्षण से किया गया था। यह दवा मस्तिष्क में कोर्टिसोल को नियंत्रित करके काम करती है, और कंपनी का कहना है कि यदि परिणाम सकारात्मक रहे तो यह मरीजों और उनके परिवारों के लिए एक महत्वपूर्ण उपचार साबित हो सकती है।

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